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Haer Family Symposium: Cameron McIntyre

Part of the Haer Family Symposium: Neuroscience Lecture Series

Presenter: Cameron McIntyre, Ph.D. of Biomedical Engineering

  • Tilles-Weidenthal Associate Professor in the School of Medicine, Department of Biomedical Engineering, Case Western Reserve University

Presentation: Engineering the Next Generation of Neuromodulation Technology

Deep brain stimulation (DBS) has evolved into a powerful clinical therapy for a range of neurological disorders, but even with impressive clinical growth, DBS technology has been relatively stagnant over its history. However, enhanced collaborations between neural engineers, neuroscientists, physicists, neurologists, and neurosurgeons are beginning to address some of the limitations of current DBS technology. These interactions have helped to develop novel ideas for the next generation of clinical DBS systems. Therefore, this presentation will collate some of that progress with two goals in mind. First, provide a general description of current clinical DBS practices, geared toward educating neural engineers on a field that needs their expertise and attention. Second, describe some of the new technological developments that are currently underway in surgical targeting, stimulation parameter selection, stimulation protocols, and stimulation hardware.

About the Haer Family Symposium: Neuroscience Lecture Series

This year’s symposium takes as its inspiration the lives of Thiel alums Fred and Jill Haer, whose various companies have advanced neuroscientific research and helped to develop new neurological and psychiatric therapies. And, true to the college’s missions, the Haers have created opportunities for Thiel College students to grow as learners and citizens.

About the Presenter, Dr. Cameron McIntyre

The Tilles-Weidenthal Associate Professor in the School of Medicine, Department of Biomedical Engineering of Case Western University, Dr. McIntyre has made remarkable contributions to brain engineering by developing devices and software that have led to improved neurological and psychiatric treatments. He also applies engineering principles and approaches to the study of brain function, because he believes that doing so brings mathematical rigor and insight to empirical research findings.

Dr. McIntyre received his BS and PhD in Biomedical Engineering from Case Western Reserve University in 1997 and 2001, respectively. His doctoral research focused on the biophysics of the interaction between electric fields and neurons. From 2001 to 2003, Dr. McIntyre underwent postdoctoral training at Johns Hopkins University and Emory University, where he studied deep brain stimulation (DBS). In 2003 he joined the faculty at the Cleveland Clinic Foundation and maintained a laboratory there until 2012. In 2013 the McIntyre lab moved to Case Western Reserve University to become the Case Neuromodulation Center. Financial support for his lab has come from numerous National Institutes of Health research grants that focus on the neurophysiological effects and engineering design of DBS systems. The fundamental goal of the research program is to bring the knowledge of DBS’s therapeutic mechanisms to bear on engineering the next-generation DBS technology. The McIntyre lab invented the GUIDE DBS clinical programming system, which Boston Scientific Neuromodulation Corporation has since commercialized, and which has won CE Mark approval in Europe.


Julie Graubard